Would you take a 'Stay Sober' pill on a night out?
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I don't know about you, but I was pretty amazed to read today that:
"Australian scientists found that a type of immune response in the brain is linked to how we respond to alcohol, and it's this response that's behind the 'behavioural changes' associated with drinking too much, such as stumbling and slurred speech".
Apparently this is likely to lead to a pill will allow the person consuming the alcohol to 'stay sober', essentially 'getting drunk' could quickly become easily avoidable.
This is made from a version of the drug naloxone which blocks the actions of toll-like receptors on glial cells, a cell type involved in the brain's immune response. Experiments conducted on mice apparently showed impressive results as Dr Mark Hutchinson explains below:
"The results showed that blocking this part of the immune system, either with the drug or genetically, reduced the effects of alcohol," said Dr Mark Hutchinson, one of the study authors.
He said he believed a similar treatment could work in humans.
"Medications targeting this specific receptor - toll-like receptor 4 - may prove beneficial in treating alcohol dependence and acute overdoses," he said.
Now I love the idea this could be used to help people with problems such as 'alcohol dependence' or 'acute overdoses', but can't help wondering where this would stop. Will people feel pressured socially into taking one of these 'stay sober' pills before they go out for the evening? If so wouldn't that be a pretty boring night out as everyone would be completely serious with no loss of inhibitions that allowed them to let their hair down and have a fun time? Isn't part of the fun of a night out the part where you not only get inebriated yourself, but get to watch your friends doing the same. The laughter flows and often result in some of the best nights out ever.
I don't know about you, but personally I find most alcoholic drinks don't actually taste all that great anyway, and I like a lot of people (if not most people), drink them more because of the effect they have, not in spite of. If I knew that by drinking a glass of wine or a pint of cider I was going to experience no sensation of relaxation or being mildly tipsy, I would probably choose a pint of lemonade and lime or a glass of orange juice instead, after all, they taste much nicer.
I could almost see a benefit to those people who had to drive on their nights out, but then I reminded myself that this does not change the fact most beer, lager, ales and spirits taste pretty rank if you disregard the actual pleasantly woozy feeling you are left with after drinking them. This means that most drivers would probably still opt to have a soft drink on the nights where they were the designated driver, as opposed to drinking something that doesn't taste as nice as a soft drink, and any positives about it have been chemically 'neutered' by a 'stay sober' pill.
I am curious to know out of those people reading this article, how many would take a 'stay sober' pill if they were going on a night out. Would they take it to avoid making a fool of themselves, or would they prefer to just not drink alcohol? Would they rather enjoy the effects of the alcohol without any pill that took those effects away? If they were driving that night would they rather restrict the alcohol they consume to within legal limits and not take the 'stay sober' pill, or would they prefer to drink plenty of alcohol having taken the 'stay sober' pill, knowing that it would have no effect on them at all? I have posted a poll at the end of this article in order to gauge the popular answers to these questions.
Of course the most amazing thing of all is that this discovery has been made by 'Australian Scientists', who I would have thought were very fond of their beers and would hate a 'stay sober' pill LOL.
Would you take a 'Stay Sober' pill if you were going on a night out?
See results without votingIf you were worried about making a 'fool of yourself' due to alcohol would you rather
See results without votingWould you take a 'stay sober' pill if you were planning to drive on a night out?
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Hmmm...
Funnily enough, although I enjoy my beer and whisky, the first point which springs to mind is a medical one...
Alcohol is a poison and drunkenness is essentially a form of poisoning. If this substance counteracts drunkenness, does it mean that people would be capable of drinking enough alcohol to kill themselves before they fall down drunk...???
Sorry, Misty, I'm an old fashioned guy, who (sometimes!) knows his limits and wants nature to remind him of them in the long established fashion...! ;)
Interesting Missy - you can write it! Useless product as people like the effects, not the actual drinking. The best thing that happened to me was when i realized booze was the enemy and I no longer needed to get half poisoned and stupid to have a good time. (After 30 years as an annoying drunk) Voted up for interest Bob
I am a tea-tottler. I have no desire for alcohol or drugs, therefore I would have no need for such a pill, but I understand where you're coming from though and if there were such a pill I would definitely reccommend it to my friends that drink.
I'm with Gordon. I suspect many drunks *would* take the stay sober pill and end up in the morgue after a night out.
And yes, I'm guessing this drug, which of curse it IS, is just another gimmick to fill the coffers of BigPharma with NO thought to how many COFFINS it might fill as a result.
Naloxone sounds scarier than alcohol. I can't see the value myself even for alcohol abusers as too much drinking will still rot your liver.
I certainly would not take the stay sober pill. I drink to become happier, lower my inhibitions, decrease shyness, become more accepting, increase my confidence and feel all round a whole lot better about life and the stay sober pill would stop that. I know my limitations, when to slow down and when to stop. I don't drink every day. Nah....no pills for me. I mean I may get addicted.
I completely agree with JamaGenee. There are already too many pills for too many things. I would never take this pill under any circumstances. There are too many sensible alternatives. It is time we resorted to strong will power. and sound decision making. This is an interesting hub and I will follow to see the continued results of your poll. Thanks mistyhorizon2003.
From a purely business persprective I can see the value of a sober pill, where you, of neccessity, attend many functions and drinking with dinner, or a drink or two to netwiork are almost obligatory. However you do need to retain your perspective and you still have to get home. Drink and drive is not a safe option, especially where long distances and no public transport are an issue.
This idea certainly has merit.
sixty - The business use is clever. It would alos be clever to use it during poker games where others drink and lose concentration. It would be great if youth could carry one of the pills with them and take it if they felt they were to be in a situation where friends or older kids demand that they drink. Some abusive spouses insist their mate drink with them, so the pill would be handy for the second person as well - to use to escape.
I don't drink because of bad experiences with people that abuse drugs and alcohol, so I'd not have use for the pill. One of my bosses used to disguise ginger ale as a drink with a Marischino cherry and a paper umbrella.
No, I wouldn't take this. I don't want to take unnecessary drugs, which no doubt have their own side effects. And on the rare occasion where I get to go out, I want to feel the effects of my drinks, and get merry!
Exactly. There are too many ways to get around being forced to drink alcohol. Plain orange juice looks the same as a Screwdriver, water and an olive looks the same as a martini. The trick is to remember to look and act a bit "happier" as the evening progresses. ;D
It won't happen any time soon! this class of drug was developed in the 60's, is strictly prescription only and has enough side effects so that it just won't be an attractive option. headaches, nausea, depression, constipation...quite a long list of stuff that will turn off most people who don't have a problem with alcohol addiction. also, it greatly reduces the craving for drugs and alcohol.
mistyhorizon2003: Fascinating! I have to wonder, though, while the effects of alcohol would be negated it would seem that the alcohol would still have to be processed through your body, wouldn't it still do damage to your liver? Also, wouldn't it still be possible to drink enough to do permanent damage to yourself? I can imagine that there would be uses for a drug like this, but I can't see myself taking it. I enjoy going out and having a few beers and I like the taste of a well-crafted brew.
Well I know I would definitely just say no to this!
I'm sure such a pill would be welcomed by many, but whether it would be a good idea is another matter - getting drunk I guess is a good warning that you've had too much alcohol to drink. Staying sober might encourage people to drink far more than is good for their livers. too much alcohol also dehydrates the body.
Anyway, for me a 'stay sober' pill would be the complete opposite of what I would want. Being rather introverted socially, I feel awkward and out of place when in a crowd in a bar or club. I actually feel the need to lose a few inhibitions to relax and enjoy life and say and do the sort of things I want to, without feeling too embarressed.
Unfortunately, I don't much like the taste of alcohol, so I rarely get to that state. Now if someone can give me a pill that makes me, not drunk, but just a little 'light-headed', then yes please!






















RealHousewife Level 8 Commenter 7 months ago
Yeah I can think of reasons where a stay sober pill could be good but the alcoholics who need them probably wouldn't take them. I also only drink on occasions and I do so to get drunk! Lol. I like beer but that's about it other than a rare mimosa.
I worked on some research studies for the purpose of approving drugs for the FDA - uh uh uh. I wouldn't take a pill unless I had to!
I think this is just another good example of the pharmaceutical companies coming up with a money maker.